A journey through the exocytic pathway.

The poster is composed of three panels, which represent the three major protein families required for the journey of cargo through the exocytic pathway. These families are the ARF and Sar1 family GTPases, which are involved in vesicle formation (left panel), Rab family GTPases, which are involved in vesicle targeting (middle panel) and SNARE family proteins, which participate in vesicle fusion (right panel). The upper half of each panel illustrates the localization of these proteins to their respective transport steps and/or compartments. In both the upper and lower panels, the mammalian proteins are labeled in black and yeast proteins are labeled in blue. If the mammalian and yeast proteins utilize the same nomenclature, they are highlighted in green. The numbers within the red circles refer to additional effectors (shown in the lower half of each panel) that participate in the indicated transport step.